Does microneedling with PRP hurt?

Most people feel pressure and some sensitivity rather than sharp pain, since numbing cream is applied first and given time to work. Certain areas can be more sensitive than others, and a good provider adjusts as they go. The PRP blood draw is quick, similar to routine bloodwork.

How long does the appointment take?

Plan for the full visit—set aside two hours for the blood draw, numbing, and the treatment itself.

How many sessions will I need?

Microneedling is typically done as a series rather than a one-time treatment. Sessions are usually sold in a package of three, spaced about five to six weeks apart, which gives your skin time to respond between visits for maximum benefit. Your provider will recommend a plan based on your skin and your goals.

What is PDRN, and why is it added?

PDRN is included for its role in skin recovery and rejuvenation. Along with PRP, it is worked into the treatment to support your skin's natural repair process. Your provider can explain whether it is a good fit for your goals.

How do I prepare for microneedling?

In general, pause strong actives like retinoids and exfoliating acids beforehand, avoid sun exposure, stay hydrated, and arrive with clean skin and no makeup. Have your aftercare products ready before you come in. Typical guidelines: avoid vitamin E, fish oil, and Ginkgo Biloba for one week prior; avoid aspirin and medications containing acetylsalicylic acid for two weeks prior; avoid antihistamines and anti-inflammatory drugs for one week prior; stop laser hair removal, electrolysis, waxing, and depilatory creams for one week prior; stop topical retinoids one week prior; and if you are using Accutane, a three-month waiting period after discontinuing is required. Do not stop any prescribed medication without checking with your prescribing doctor, and always confirm your prep with your provider.

What is the downtime and aftercare?

Your skin may look flushed for a day or two. Keep your routine gentle, skip makeup for about the first day, avoid heavy sweating and intense exercise for a day or two, and be diligent with sun protection. If your schedule is busy, plan to lay low for the first 48 hours.

Can I play sports or work out afterward?

It is best to avoid intense exercise and heavy sweating for a day or two, since sweat and sun can work against your results. If you are active outdoors, build a short break and sun protection into your plan before you book.

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Achieving your best skin doesn't stop when you leave our spa—that is why we created this space. Explore our latest articles covering emerging Med Spa trends, seasonal skincare guides, and professional advice on what actually works.

Marina Girgis, BS, RN 7/26/26 Marina Girgis, BS, RN 7/26/26

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