While both treatments are designed to repair and "biostimulate" your skin, they come from different sources:

• PRP (Platelet-Rich Plasma): This is "autologous," meaning it comes from your own blood. We spin it in a centrifuge to concentrate growth factors that trigger healing. It is the ultimate natural "Vampire Facial."

• PDRN (Salmon Sperm DNA): This is a bio-active DNA fragment (Polynucleotide). It doesn't require a blood draw and provides a highly consistent, medical-grade "repair signal" to your cells. It is the gold standard for deep hydration and fixing chronic skin inflammation.

This is one of our most common questions in Torrance.

• Choose PDRN if you have "crepey" skin, fine lines, or dark circles. PDRN is famous for its "DNA-repair" ability, making it incredible for thickening the delicate skin under the eyes.

• Choose PRP if you are looking for volume and a more "holistic" approach to hollow tear troughs.

Absolutely. Despite the viral name, PDRN is a highly purified medical ingredient that has been used in wound healing for decades. It is biocompatible with human DNA and is specifically designed to be "non-immunogenic," meaning the risk of an allergic reaction is extremely low. It is one of the safest ways to achieve a "glass skin" glow in 2026

Yes! This is what we call the "Total Regeneration Protocol." At South Bay Med Spa, we often use Eclipse PRP to provide the initial "boost" of growth factors and then layer in PDRN to ensure long-term cellular repair and hydration. Combining them often leads to faster healing and more dramatic "lifting" effects than using either one alone.

Because these treatments are "biostimulators" (meaning they make your body do the work), the results aren't instant like filler, but they are much more natural:

• PRP: You’ll see a glow within 2 weeks, with collagen building for 3–6 months.

• PDRN: You often notice improved hydration within days, with skin "firming" appearing after a series of 3 treatments.

• Maintenance: We typically recommend a "refresh" session every 6–12 months to keep your collagen levels peaked.